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Pycnogenol®+ is a synergistic formula of Pycnogenol bark extract from the French maritime pine, combined with extracts of beetroot and grape olive. Studies suggest that the natural compounds in Pycnogenol+ support normal nitric oxide production, which may help with blood flow through the brain and body. Pycnogenol+ also acts as an antioxidant that protects cells from age-related oxidative stress.